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Common themes include rapid onset of anti-inflammatory effects (often within days), gradual improvement in function over weeks, and best results when combined with appropriate physical therapy and lifestyle modifications

[3] Discontinuing or interrupting a proven cardiovascular therapy to add an unproven antioxidant supplement is not supported by evidence

Either dysfunctions or hyperfunctions are implicated in a variety of disorders, particularly congenital sensory neuropathy, sensory neuropathy caused by diabetes, herpes zoster, postherpetic neuralgia, atopic dermatitis, impaired healing of injured tissue (e.g