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The sc infusion was necessary because the GLP-1 molecule is cleared extremely rapidly in the body (intravenous (IV) half-life of 1-2 min.) due to the actions of an enzyme, dipeptidyl peptidase 4 (DPP-4), which inactivates the peptide [13]

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Weight-loss medications may be covered for individuals whose BMI is 35 or greater, or 30 and above with a qualifying health condition like diabetes, hypertension, or dyslipidemia