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de Lecea L et al

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Chronic tinnitus is closely associated with increased spontaneous neuronal firing rates, broadened tuning curves, and map reorganization in the cortical area representing the damaged frequency in AC (De Ridder et al., 2014

Research indicates that the primary mechanism by which cisplatin damages renal tubular and glomerular cells is by inducing oxidative stress, which results in cell necrosis and apoptosis, vascular defects, and robust immune response [7]