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For the side effect phenotypes, we defined separate casecontrol phenotypes for each side effect recorded in the survey, contrasting those who self-rated their side effects as moderate or severe (cases) to those who self-rated their side effects as mild or non-existent (controls)

Cagrilintide offers a focused, amylin-based strategy with milder side effects and strong combination therapy potential

Semaglutide Major trials demonstrated an average weight loss of between 15 and 17 percent of the participants starting weight over a 68-week time frame

Common side effects Gastrointestinal side effects: GI-related side effects are the most commonly reported in patients taking semaglutide because of the drugs GLP-1 action