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Full-length thymosin beta-4, formulated as a topical ophthalmic solution (RGN-259), has been evaluated in genuine Phase II randomized, placebo-controlled human trials for dry eye disease

Chien PFW, Smith K, Peter WW, Scrimgeour CM, Talor DJ, Rennie MJ: Protein turnover in the human fetus studied a term using stable isotope tracer amino acids

Growth hormone-releasing peptides like sermorelin amplify TRT's muscle-building and recovery benefits, while BPC-157 supports tissue repair in active patients

Any use involving human participants requires appropriate institutional review board or ethics committee oversight, and compounds being tested in humans outside of approved cosmetic or over-the-counter frameworks require investigational new drug authorization