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Whilst anxiety is not listed as a recognised side effect in official regulatory data from the MHRA or clinical trials, occasional patient reports have raised questions about this potential link

measured the GSH levels in the stratum corneum of the subjects and found that GSH in stratum corneum in acne patients was significantly lower than that of healthy controls.[] ROSACEA The UV radiation is a very well-known triggering and aggravating factor for rosacea.[] It is a potent inducer of ROS generation in the skin.[] In patients of rosacea, there is an increased ratio of oxidized to reduced glutathione compared with healthy subjects.[] A pilot, prospective, two-center, assessor-blinded study by Dall'Oglio et al

Without sufficient glutathione, melanin regulation gets disrupted, leading to hyperpigmentation or uneven spots

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