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Once-weekly Tirzepatide Versus Once-daily Insulin Degludec as Add-on to Metformin With or Without SGLT2 Inhibitors in Patients With Type 2 Diabetes (SURPASS-3): A Randomised, Open-label, Parallel-group, Phase 3 Trial.

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Signs and symptoms include abdominal pain that may radiate to the back, nausea and vomiting, fever, and bloating