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research focuses on the effects of short-term exposures or low-concentration exposures on aquatic organisms, and long-term ecological monitoring of SSRIs is rarely performed, and there have been few cross-species studies that have investigated the effects of short-term or low-concentration exposure on aquatic organisms

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Candidates for such intrinsic rhythms would be hormone transport (uptake), metabolization (deiodinases), and/or receptor activation (THR and THR), leading to an integrated rhythmic response 26