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Description

The use of LC or NAC as a therapeutic for G6PD def may expand to other G6PD def -related disorders as LC increases expression of G6PD, glutamate-cysteine ligase modifier subunit (GCLM), glutamate-cysteine ligase catalytic subunit (GCLC), in G6PD def monocytes and endothelial cells [71,72]

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Dichloroacetate treatment substantially elevated the NADPH/NADP+ ratio (Figure 7A)

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