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patients should seek immediate medical attention if they develop severe, persistent abdominal pain radiating to the back Gallbladder disorders including cholelithiasis (gallstones) and cholecystitis Changes in vision temporary worsening of diabetic retinopathy has been reported with rapid improvement in glycaemic control [2] [4] The SmPC includes a precautionary warning about thyroid C-cell tumours based on animal studies, though the risk in humans remains unproven

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