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10.1084/jem.20170558 141 MedinaD

Updated in August 10, 2018

This is a multi billion dollar regulatory morass

9,10 As well as gut hormones, bone remodelling is also known to be regulated by parathyroid hormone (PTH) and influenced by various other biochemical factors, such as calcitonin, oestrogen, thyroid hormones, glucocorticoids, insulin-like growth factors (IGFs), bone morphogenetic proteins (BMPs), prostaglandins, vitamin D, and transforming growth factor (TGF-), 4,11 but the focus of this report will primarily be gut hormones