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Bahney CS, Hu DP, Taylor AJ, Ferro F, Britz HM, Hallgrimsson B, et al
380 Hedgehog pathway inhibitors The Hedgehog signaling pathway is critical for CSC self-renewal and metastatic potential, particularly in pancreatic, lung, and medulloblastoma CSCs
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Practical Formulation Considerations and Risk Mitigation While the chemical evidence does not support degradation concerns for this specific combination, reasonable formulation practices can further minimize theoretical risks: Reconstitute immediately before use when possible
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