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In terms of side effects there were twice as many gastrointestinal side effects with the treatment group as in the placebo group (30 of 51 people in the treatment group experienced them as opposed to 15 of 50 in the placebo group.) They note that The UACR reduction achieved with semaglutide is clinically relevant, as a previous meta-analysis showed that interventions that reduce albuminuria by more than 25% are associated with a high likelihood to reduce the risk of kidney failure. Im not saying that this is nothing but I do want to point out that high likelihood to reduce risk is not a very specific claim

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The standard protocol is 2mg administered subcutaneously once daily, typically in the abdominal area