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This retrospective study across 12 databases in the Observational Health Data Sciences and Informatics (OHDSI) network over a seven-year period included data on adults with type 2 diabetes on semaglutide, other GLP-1 drugs (dulaglutide, exenatide) or non-GLP-1 drugs (empagliflozin, sitagliptin, glipizide)

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In clinical trials, retatrutide has been administered via subcutaneous injection on a once-weekly basis, with doses escalating gradually over several weeks to improve tolerability