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A substantial volume of data indicates that an elevated HR is independently associated with increased cardiovascular morbidity and mortality in the general population, in subjects with cardiovascular diseases, and those with diabetes [13, 14, 38, 39]
A frank discussion about dietary patterns, portion sizes, beverage choices (particularly sugar-sweetened or alcoholic drinks), and physical activity levels can identify modifiable factors that may be limiting treatment response
Similar to cuproptosis, ferroptosis is a metal ion-dependent form of cell death, and previous studies have reported that cold-induced cell death in human cancer cells resembles ferroptosis 45
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