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Injecting rats with selenium 24 hours prior to acetaminophen overdose provided significant protection against hepatotoxicity, lowered levels of ALT and AST (markers of liver damage), and increased liver glutathione levels (Schnell 1988)

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Most reviews conclude that while the mechanistic rationale is plausible, the current evidence is insufficient to support routine use of inositol for mental health conditions.20 38 Inositol supplements appear to work by supporting intracellular signaling rather than acting as a direct hormone or drug-like agent

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