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A 2016 study found that B12 supplements that are mixed with saliva are broken down and absorbed better than supplements that are swallowed whole like capsules or soft gels

[2] [9] However, other research suggests that the proportion of people with low or marginal levels of vitamin B 12 is up to 40% in the Western world

Some patients report feeling refreshed or more energized after a B12 shot, while others may notice changes gradually over time

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