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The GLP-1-activated neurons in the brain also limit appetite for a while after a large meal (e.g., the thought of eating is unappealing for many hours after pigging out on pizza).[ref] Stress-related appetite suppression: Additionally, the GLP-1 neurons activate during times of acute stress to suppress appetite

fMRI, functional magnetic resonance imaging

So the numbers below are a useful guide , not a perfect head-to-head comparison

The longer answer which is what the rest of this guide is about explains why, what's actually in the patches, what the science says about transdermal weight loss, and what works instead if you're serious about losing weight