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Individuals with reduced bile acid reabsorption efficiency may develop worse diarrhea or cramping when GLP-1 agonists further slow transit and alter intestinal pH

Contact your healthcare provider if you experience persistent or severe gastrointestinal symptoms that interfere with your ability to maintain adequate nutrition, including prolonged nausea, repeated vomiting, severe abdominal pain, or signs of dehydration such as dark urine, dizziness, or reduced urination

they are required for the metabolism of glucose in the muscles C