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It is a hereditary, genetic disorder
The powdered rhizome of this plant, called turmeric, has been used in Asian medicine since the second millennium BC for various disorders and ailments, including abdominal pain, sprains and swelling, anorexia, rheumatism, diabetic wounds, liver disorders, cough, arthritis, wounds, tumours, inflammation, colds, asthma, bronchitis, and jaundice
reported that under stressful circumstances, MAPK acts on RBOH (Respiratory Burst Oxidase Homologs/ NADPH oxidase) and upregulates its activity and ROS generation in plants [111]