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Retatrutide is Lillys triple GLP-1/GIP/glucagon receptor agonist, in Phase 3 (TRIUMPH program) for obesity, osteoarthritis, diabetes, cardiovascular outcomes, and other indications

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A 52-week treatment with tirzepatide (5mg, 10mg, or 15 mg) led to a significant MASH resolution without worsening liver fibrosis compared to placebo (Fig.3)

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