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At the same time, the multifunctional nano-porphyrin material (P18-APBA-HA) constructed using photosensitizer-purpurin 18 (P18), hyaluronic acid, and 4-(aminomethyl)phenylboronic acid (APBA) can be inserted into the phospholipid membrane and loaded with epacadostat (EPA) to prepare a dual drug delivery system LipEPAP18-APBA-HA, which can also induce anti-tumor immunity by promoting DCs maturation, activating CD8 + T cells and inhibiting Tregs thereby suppressing tumor growth and metastasis (204)

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Stomach acid tends to decrease with age, which makes it harder to extract B12 from food

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