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Furthermore, mitochondrial dysfunction promotes NLRP3 inflammasome assembly and caspase-1 activation, leading to the secretion of pro-inflammatory cytokines like IL-1, which are associated with the aberrant activation of CDK5 [53, 54]

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Bettge K, Kahle M, Abd El Aziz MS, Meier JJ, Nauck MA

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