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Malabsorption (insufficient absorption of vitamin B 12 in the intestine), insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and required to absorb vitamin B 12 ), Diseases in the end section of the ileum (part of the small intestine), e.g

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Moreover, (iv) the addition of GSH to isolated mitochondria rapidly reduces Grx1roGFP2 in the IMS (Figure 4) and (v) the absence of Glr1 hampers the redox state recovery after oxidative shock of the IMSlocalized oxidoreductase Mia40 (Figure 8E)

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