However, current evidence is still inconclusive to demonstrate a direct negative effect of GLP-1 RAs on LBM loss, largely due to heterogeneity in study designs and the limited number of trials specifically evaluating this endpoint [77]
Brix, Laszlo Hegeds, Miyuki Hsing-Chun Hsieh, Chris Tzu-Ting Su, Michael Chun-Yuan Cheng, Zoe Chi-Jui Chang, Edward Chia-Cheng Lai, Swaleh Hussain, Cherry Chu, Tara Gomes, Tony Antoniou, Antoine Eskander, Zachary Bouck, Mina Tadrous, Sungho Bea, Eun-Young Choi, Ju-Young Shin, Karin Modig, Mats Talbck, Rickard Ljung, Hanne Lvdal Gulseth, ystein Karlstad, Blnaid Hicks and Anton Pottegrd, 16 January 2025, Thyroid
A study published examining lean mass preservation during GLP-1 therapy found that participants who consumed adequate protein and engaged in resistance training three to five days per week achieved significantly better body composition outcomes compared to those who did not prioritize protein
Its important to get it under professional supervision to stay safe
