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To evaluate the structural impact of G1228D mutation, we visualized the G1228 in the three Cryo-EM structures of bovine MRP1 40,44 , the apo, LTC 4 -bound and ATP-bound structures (Fig

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IgG + MBC stimulation with gp34 1-179 resulted in the activation of the PI3K/AKT/mTOR/S6 pathway in a SYK-independent manner and a subsequent delay in BCR internalization