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Epitalons ability to reactivate telomerase has been demonstrated using the Telomeric Repeat Amplification Protocol (TRAP) assay in two key cell models: HeLa cells (telomerase-positive cancer cell line) and Human fetal lung fibroblasts (602/17)

Additionally, ROS activate the hypoxia-inducible factor-1 alpha (HIF-1) pathway, leading to increased expression of vascular endothelial growth factor (VEGF) and the formation of retinal neovascularization [186]

The ~5.88.1-day half-life comes from the DAC version, which binds albumin

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