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Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat

The National Cancer Institute ( lists a number of on-going clinical trials involving metformin for the following: Her2 positive breast cancer, head and neck squamous cell cancer, endometrial and ovarian cancers, multiple myeloma, lymphocytic leukemia, and thyroid cancer

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Look for trials that say 'Recruiting.' You typically need a BMI of 30 or higher (or 27+ with a health condition like high blood pressure)