Smooth, controlled administration with an appropriately sized needle is always the gold standard
It is converted to coenzyme B12 in the body and in this form facilitates the conversion of homocysteine to methionine (methylcobalamin) and plays an important role in converting methylmalonyl-coenzyme A to succinyl-Co-A (fatty acid and amino acid metabolism)
Rollins B, Martin MV, Sequeira PA, Moon EA, Morgan LZ, Watson SJ, et al
Skin Rejuvenation and Anti-Aging Protocol Dose: 1 to 2 mg per day Route: Subcutaneous (abdomen, thigh, or upper arm) Frequency: Daily, 5 days on, 2 days off Cycle: 8 to 12 weeks on, 4 weeks off Expected results: 4 to 8 weeks for visible improvement Best for: Fine lines, skin elasticity, skin density, overall skin quality In a 12-week facial cream study (human trial, 71 women), 70% showed increased collagen production with GHK-Cu, compared to 50% with vitamin C and 40% with retinoic acid (Pickart et al., 2015)