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Many titration schedules increase to 12 mg over 8-12+ weeks, though some trial arms used faster or slower steps
The ultimate goal is to transition from theoretical risks based on animal data to communicable risk intervals based on population data, providing a quantifiable basis for periconception risk counseling
But because they reduce appetite and slow digestion, they can also increase the risk of nutrient deficiencies and muscle loss, which come along with a number of side effects
The FDA has also warned that some compounded semaglutide products may use salt forms - semaglutide sodium or semaglutide acetate - which are chemically different from the active ingredient in FDA-approved semaglutide products
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