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Hypotension consider reducing antihypertensive medicines before initiating treatment or before a dose increase Diabetic ketoacidosis (DKA) increased risk (see below) SGLT-2 inhibitor use is associated with an increased risk of severe DKA People taking SGLT-2 inhibitors are at increased risk of DKA, particularly in the first few months of treatment or peri-operatively

Many people feel a sense of failure when they miss a dose, leading to a might as well give up for the week mentality

Tumor growth in patients with tuberous sclerosis complex on the ketogenic diet