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But the Phase 3 TRIUMPH-4 trial, which ran for 68 weeks, showed an average reduction of 28.7% at the same 12 mg dose

Establish a regular eating schedule within a consistent window each day, ideally 12 hours

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For some conditions, the evidence is now strong: large, late-stage human trials (Phase 3, the kind regulators require before approving a drug) agree with the smaller, earlier trials that preceded them (Phase 2)