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The amount of glutathione in the sample may be low

Borges Filho C, Jesse CR, Donato F, Del Fabbro L, de Gomes MG, Goes AT, Souza LC, Giacomeli R, Antunes M, Luchese C, Roman SS (2016) Neurochemical factors associated with the antidepressant-like effect of flavonoid chrysin in chronically stressed mice

Others might theoretically conflict with metabolic pathways already being modulated