B1 (Thiamine): 1.2 mg B2 (Riboflavin): 1.3 mg B3 (Niacin): 16 mg NE (Niacin Equivalents) B5 (Pantothenic Acid): 5 mg B6 (Pyridoxine): 1.3 mg B7 (Biotin): 30 mcg B9 (Folic Acid): 400 mcg B12 (Cobalamin): 2.4 mcg Children and Teens: The doses children and adolescents need are typically lesser, and should be more appropriate in quantity and based on age and body mass: 1-3 years: about 50% or so of adult dosing 4-8 years: 60-70% of adult dosing 9-13 years: 80-90% of adult dosing 4-18 years: Adult dosing Pregnancy and Breastfeeding: Pregnant or breastfeeding women may need increased dosages, particularly B9 for preventing birth defects and B12 to ensure proper growth of the fetus
Guideline on immunogenicity assessment of therapeutic proteins
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T4 helps to promote angiogenesis, or the formation of new blood vessels needed by fast-growing tumors