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6,7 Learning objectives: Recognize the prevalence and clinical impact of obesity in PsA Understand mutually reinforcing mechanisms shared between obesity and PsA pathogeneses Explore evidence on how weight interventions Concomitant obesity may decrease the likelihood of achieving PsA treatment goals GRAPPA treatment goals include achieving the lowest possible level of disease activity in all domains of disease 8 However, up to 70% of patients do not achieve MDA by 6 months of TNFi treatment 9 Patients with persistent symptoms despite at least one adequate trial of a targeted-synthetic or biologic DMARD may have complex-to-manage PsA 10 For these patients, comorbidities may contribute to inadequate treatment response

Ramakrishnan, A

Consequently, dietary modification emerges as a potentially simple and relatively low-risk strategy to mitigate TMAO-associated IBD