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Chandys hypothesis, that the rapid onset of the repairing processes induced by B12 shots might overwhelm the system and temporarily cause a worsening in symptoms, similar to the Jarisch-Herxheimer reaction in those treated for Lyme disease

5 , zqae005 (2024)

In addition, during the whole MD simulations, the particle mesh Ewald (PME) 38,39 method was employed to control the long-range electrostatic interactions and the cutoff value of van der Waals interaction was set as 12

Conversely, Sarma et al