676 The oncogene c-Myc directly upregulates a suite of glycolytic genes (HK2, PFK1, TPI, GAPDH, ENO, LDHA, and MCT1), intensifies glycolytic flux in cancer cells, 663,677,678 and stabilizes HIF-1 under normoxic conditions by inhibiting its proteasomal degradation through interaction with the von HippelLindau protein
Retains the C-terminal lipolytic domain of HGH without the growth-promoting IGF-1 elevation
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