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As GLP-1 RAs are increasingly used in the treatment of T2DM, their potential carcinogenic and antineoplastic effects should be further investigated in future clinical studies

Pharmaceutics 16 (7), 852

Methods Animals and housing conditions Experiments were performed in accordance with the Animal Protection Law of the European Union after permission by the Governments of Upper Bavaria, Germany, or Copenhagen, Denmark, or by the Institutional Animal Care and Use Committees of the Universities of Texas Southwestern, Michigan, Duke or Yale, USA

Do not use orforglipron (Foundayo) if you have a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2 syndrome