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At this time, immunotherapy shows great potential in a variety of tumor clinical treatments, however, its clinical effect in glioma is limited because of tumor immune privilege which was induced by the glioma immunosuppressive microenvironment, so remodeling the immunosuppressive microenvironment is a practical way to eliminate glioma immunotherapy resistance

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The mean serum AST, ALT, ALP, direct bilirubin, total bilirubin, PT, PTT, and GGT before and after intervention were compared within groups using the independent sample t -test