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moreover, significant weight loss reduces the requirement for procedures, such as coronary artery bypass grafting, carotid endarterectomy, and percutaneous coronary intervention, as well as peripheral vascular disease, and total mortality by up to 24% [89, 90]

Recent results from the AMPLITUDE-O trial with efpeglenatide64 suggest that the cardiovascular benefits of this family are not exclusive of the human GLP-1 analogs

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