Medications Statins (first-line) Ezetimibe, PCSK9 inhibitors Fibrates (for triglycerides) LDL = main target for cardiovascular risk reduction HDL protective, total cholesterol alone is less informative Familial hypercholesterolemia early CAD, tendon xanthomas Cholesterol is a lipid essential for cell membranes, steroid hormones, and bile acids, with LDL increasing cardiovascular risk and HDL being protective To view or add a comment, sign in Insulin: The Master Regulator of Whole-Body Metabolism Insulin is often simplified as a blood glucose In reality, insulin functions as a central metabolic signal that coordinates energy balance, nutrient partitioning, vascular health, immune activity, and inter-organ communication
Nausea, vomiting, diarrhea, and constipation affect 40-80% of users depending on dose
the ability of serotonin to block ghrelins orexigenic effects (Currie et al., 2010)
In a move to enhance patient safety and curb misuse, UK online pharmacies will now be required to implement stricter checks before dispensing weight-loss medications such as Wegovy and Mounjaro