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In the context of tissue remodeling, GHK-Cu exerts dual-modulatory effects on the extracellular matrix (ECM)

Untreated cells and cells treated only with the solvent (i.e., 0.1% DMSO) exhibited similar proliferation rates

3.5 GHK-Cu regulated the SIRT1/STAT3 pathway SIRT1, which is closely associated with cellular metabolism and stress responses, also interacts with the STAT3 pathway (Figures 6AD, DSS-induced mice exhibited significantly increased SIRT1 expression and decreased p-STAT3 expression compared to the Control group

Alpha-Ketoglutarate (AKG) is an organic compound that is used by the body as part of an energy cycle