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When lifestyle measures alone are insufficient, pharmacological options such as Mounjaro, Wegovy (semaglutide), or orlistat may be appropriate for eligible individuals under medical supervision

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The small second-order rate constant for the simulated reaction between GSH and the complex of reduced PfGrx C88S and roGFP2 WT (S 2 ) might reflect a poor accessibility of the 1st glutathione interaction site in this complex (Fig