dulaglutide, NEJM, 2025 Semaglutide and cartilage regeneration Cell Metabolism, 2026 Lean mass loss with GLP-1 drugs systematic review, 2024 Retatrutide Phase 2 NEJM, 2023 Myostatin gene discovery McPherron et al., Nature, 1997 German myostatin-knockout child Schuelke et al., NEJM, 2004 Myostatin inhibitor history Nielsen et al., Cells, 2021 Micronutrient joint advisory Mozaffarian et al., 2025 Last Updated on June 20, 2026 by Joe Garma
Obesity medicine physician Jessica Duncan discusses the article GLP-1 weight regain: Why stopping medication leads to weight return. Jessica explains that expecting to maintain weight loss after abruptly stopping GLP-1 therapy is unrealistic because it ignores the physiological forces that defend a persons prior weight
The calculators recommended split at 4 mg and above is every 3 days (q3d): each shot carries three-sevenths of the weekly dose across about 2.3 injections a week, which lands the per-injection peak near 43% of the once-weekly peak
CrossRef GLP-1 Receptor Agonists in Non-Alcoholic Fatty Liver Disease: Current Evidence and Future Perspectives Riccardo Nevola, Raffaella Epifani, Simona Imbriani, Giovanni Tortorella, Concetta Aprea, Raffaele Galiero, Luca Rinaldi, Raffaele Marfella, Ferdinando Carlo Sasso International Journal of Molecular Sciences.2023