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Interestingly, some evidence suggests that reduced, but not absent, GPX4 activity may be associated with increased lifespan in mice, pointing to complex interactions between oxidative stress and ageing

43 Maintaining a healthy gut microbiota through adequate dietary intake of fruits, vegetables, whole grains, legumes, and fermented foods may aid the SCD patient in optimizing host immunity

Inappropriate administration solely for aesthetic enhancement may expose individuals to unnecessary risk

All authors critically revised the manuscript, approved the final version to be published, and agree to be accountable for all aspects of the work