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Sci Rep 7:41188 Sandoval DA, DAlessio DA (2015) Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease

Cons of Thigh Injection: For individuals with very low body fat in their legs, there is a slightly higher risk of the injection feeling pinchy if it gets too close to the muscle

But its also because Americans are getting trampled by the rising price of drugs and are desperate for a solution

It is possible that Medicare could select semaglutide for drug price negotiation as early as 2025, based on its earliest FDA approval in late 2017, with a negotiated price available beginning in 2027