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ROS can further activate epithelial cells and macrophages facilitating neutrophil, monocyte, and lymphocyte recruitment, and the recruited activated inflammatory cells subsequently enhance additional ROS generation, increasing the pro-oxidant burden (8085)

Increased serum coagulation factors and type 1 diabetes Prothrombin (F2) was more abundant in the ND individuals relative to the UFMs, and was similarly reported in the serum proteomics study by do Nascimento de Oliveira et al [9]

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