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What users typically report: Sleep quality improvements become more consistent (less night-to-night variation) Night waking decreases particularly the 2-4am waking associated with cortisol surges Morning energy is noticeably improved Recovery from physical activity feels enhanced (growth hormone release during deep sleep is improved) Anxiety before sleep may be reduced, particularly in stress-driven insomnia By the end of week 1, the picture is usually clear: Whether someone is a DSIP responder

She completed Pharmacy Practice Residency training at the University of Pittsburgh/VA Pittsburgh Healthcare System

Individuals with renal impairment represent the highest-risk group

Normal eGFR varies by age and decreases as you get older, but a higher number is better, typically equal to or above 60