Nat Commun 8:1177 Arbour KC, Jordan E, Kim HR, Dienstag J, Yu HA, Sanchez-Vega F, Lito P, Berger M, Solit DB, Hellmann M, Kris MG, Rudin CM, Ni A, Arcila M, Ladanyi M, Riely GJ (2018) Effects of co-occurring genomic alterations on outcomes in patients with KRAS-mutant non-small cell lung cancer
Pathophysiology dictates that tissue heals only when mechanics, metabolism, and microcirculation harmonize
In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]
Martini G, Toniolo D, Vulliamy T, Luzzatto L, Dono R, Viglietto G, et al