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10.1039/c8fo00168e 16 DengY.WangL.YangY.SunW.XieR.LiuX.et al (2013)

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(2018) using inducible pluripotent stem cells (iPSC)-derived neurons with triplication of SNCA gene showed that oligomeric -synuclein through inhibition of mitochondrial complex I activity caused oxidation of a subunit of ATP synthase leading to the opening of mitochondrial permeability transition pore with consequent mitochondrial swelling and cell death